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For neuroinflammation, others have demonstrated elevated levels in PLWH compared to HIV- controls [19,20,21], while we demonstrated that HIV- cigarette smokers who smoked to satiety [37] or underwent overnight abstinence [38] had lower whole brain (WB) standardized uptake values (SUVs) on PET scanning than HIV- non-smokers (15.517.0% across studies), indicating reduced neuroinflammatory function from smoking

J Alcohol Drug Depend

Clearly, however, these people never heard of the Laffer curve, despite it being the basic economic premise behind such "sin taxes." Simply put, the Laffer curve argues that there is a point where a tax rate can be so high, it actually collects less revenue by encouraging individuals to avoid the behavior or product being taxed